Shielded Coaxial Optrode Arrays for Neurophysiology

Shielded Coaxial Optrode Arrays for Neurophysiology

Recent progress in the study of the brain has been greatly facilitated by the development of new tools capable of minimally-invasive, robust coupling to neuronal assemblies. Two prominent examples are the microelectrode array (MEA), which enables electrical signals from large numbers of neurons to be detected and spatiotemporally correlated, and optogenetics, which enables the electrical activi...

A coaxial optrode as multifunction write-read probe for optogenetic studies in non-human primates.

BACKGROUND Advances in optogenetics have led to first reports of expression of light-gated ion-channels in non-human primates (NHPs). However, a major obstacle preventing effective application of optogenetics in NHPs and translation to optogenetic therapeutics is the absence of compatible multifunction optoelectronic probes for (1) precision light delivery, (2) low-interference electrophysiolog...

Enhanced mid-infrared transmission through nanoscale metallic coaxial-aperture arrays.

Using a single interferometric lithography patterning step along with self-aligned pattern-definition techniques, uniform, large-area metallic coaxial arrays with ~ 100-nm toroidal gaps are fabricated. Enhanced (5x) mid-infrared (4 mum) transmission through these sub-wavelength coaxial arrays is observed as compared with that through the same fractional opening area hole arrays as a result of t...

Silicon nitride photonics for optogenetics: Design and fabrication of in vitro and in vivo multi-electrode-optrode arrays for optogenetics

Coaxial PANI/TiN/PANI nanotube arrays for high-performance supercapacitor electrodes.

Coaxial PANI/TiN/PANI nanotube arrays prepared by electrochemical polymerization of PANI on nanoporous TiN nanotube arrays exhibit a high specific capacitance of 242 mF cm(-2), excellent rate capability with the capacitance remaining at 69% when the current density is increased 50 times from 0.2 to 10 mA cm(-2), and a long cycling life with less than 0.005% decay per cycle.